Esomeprazole Magnesium Trihydrate API&Pellet

Esomeprazole Magnesium Trihydrate Manufacturers in India - APIs&Pellets 1

Product Description:

  • Therapeutic Category : Antiulceratives
  • CAS Number : 217087-09-7
  • Molecular Formula : C34H36MgN6O6S2.3H₂O
  • Molecular Weight: 767.2 g/mol
  • Mesh Size : As per Customer Requirement
  • Form : Tablet ,Capsule, granule, Injectable, Powder
  • Metrochem Development Status : Commercial

Metrochem API Pvt Ltd is a quality-driven Esomeprazole Magnesium Trihydrate API&Pellet Manufacturers in India.Our manufacturing facility is designed to meet best safety standards.Our products are tested in laboratory and meets the international standards for identity, purity and composition.We are committed to manufacture and supply high quality products to our customers at best price.Our continuous enhancement of the cost reduction cycle to ensure long-term sustainability for various companies.

Mechanism of Action:

Esomeprazole Magnesium Trihydrate is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+ /K+ -ATPase in the gastric parietal cell. The S- and R-isomers of omeprazole are protonated and converted in the acidic compartment of the parietal cell forming the active inhibitor, the achiral sulphenamide. By acting specifically on the proton pump, esomeprazole blocks the final step in acid production, thus reducing gastric acidity. This effect is dose-related up to a daily dose of 20 to 40 mg and leads to inhibition of gastric acid secretion.


Esomeprazole Magnesium Trihydrate is a prescription drug and proton pump inhibitor(PPI), indicated for the following:

  • Treatment of gastroesophageal reflux disease (GERD)
  • Risk reduction of NSAID-associated gastric ulcer 
  • pylori eradication to reduce the risk of duodenal ulcer recurrence
  • Pathological hypersecretory conditions, including Zollinger-Ellison syndrome

Metrochem API Expertise:

Metrochem API Pvt Ltd is a leading manufacturer and supplier of Active Pharmaceutical Ingredients (APIs) through our manufacturing sites in Hyderabad and Vizag. Our API facilities have been inspected and approved by several global regulatory bodies including the US FDA, Japan PMDA, KFDA, and meet the cGMP compliance standards. Adapting quickly to the ever-evolving demands, we have emerged as one of the fastest growing organization in the pharmaceutical industry across the India. To cater our customer high volume requirements, we have dedicated each of our 6 manufacturing facilities to our 3 core product groups – APIs, Pelletization& Intermediates – reinforced by a well equipped, centralized Research & Development laboratory.

We have been successfully supplying APIs all over the globe for more than 15 years. Total reactor volume exceeds 1200 KL which includes pilot and multi-purpose units. We are capable of executing extensive API requirements for our customers. Metrochem API Pvt Ltd has an experienced team of highly skilled chemists, experienced regulatory professionals and supply chain experts, who are ready to handle your API manufacturing requirements with expert care. We also offer Contract Manufacturing, Contract Research, and Custom Synthesis services. We have a stand-alone R&D center located in Hyderabad with State-of-the-art analytical facilities and over 90 scientists.We have extensively worked on and delivered new products across a wide variety of therapeutic segments and as a company, we have built strong expertise in new product development.

Disclaimer : Metrochem API Pvt Ltd respects the intellectual property rights of others. Some of the Active Pharmaceuticals Ingredients (APIs) listed in the Metrochem’s product list or brochure or in the product list uploaded in Metrochem’s website may be protected by a valid patent in India or in any other countries concerned. However, mentioning of the name of such product(s) in the product brochure or the product list shall not be construed as infringement in any manner whatsoever. Without prejudice to the foregoing, Metrochem’s supply of API being protected by a valid product patent, if any, is intended solely for uses reasonably relating to the development and submission of information required under any law for the time being inforce, in India, or in a country other than India that regulates the manufacture, use, sale or import of the said product, strictly under the conditions as set forth in Section 107A of the Indian patents Act, 1970, as amended in 2005, or an equivalent provision (Bolar exemption) thereof in a country other than India. The disclaimer is applicable till the expiration of the corresponding product patent(s), if any, in the respective. countries concerned.  None of the products will be supplied to the countries wherein this could be in conflict with existing laws. However, the final responsibility lies exclusively with the buyer/ultimate customer.

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