- Therapeutic Category : Antithrombotic / Anticoagulant
- CAS Number : 503612-47-3
- Molecular Formula : C25H25N5O4
- Molecular Weight: 459.5 g/mol
- Mesh Size : As per Customer Requirement
- Form : Tablet
- Metrochem Development Status : Commercial
Metrochem API Pvt Ltd one of the largest Apixaban Manufacturers in India. We supply competitive prices and deals with bulk orders from various customers around the world .Technically we have the most advanced manufacturing facilities and our whole production cycle is in line with regulatory policy.
Mechanism of Action:
Apixaban is a selective inhibitor of FXa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound FXa, and prothrombinase activity. Apixaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, apixaban decreases thrombin generation and thrombus development.
Apixaban is used to prevent the formation of serious blood clots due to some irregular heartbeat (atrial fibrillation) or after hip/knee replacement surgery.With atrial fibrillation, Part of the heart does not beat as it should.This may result in the formation of blood clots, which may travel to other parts of your body (such as the lungs or legs) or increase your risk of stroke.
Metrochem API Expertise:
Metrochem API Pvt Ltd is a leading manufacturer and supplier of Active Pharmaceutical Ingredients (APIs) through our manufacturing sites in Hyderabad and Vizag. Our API facilities have been inspected and approved by several global regulatory bodies including the US FDA, Japan PMDA, KFDA, and meet the cGMP compliance standards. Adapting quickly to the ever-evolving demands, we have emerged as one of the fastest growing organization in the pharmaceutical industry across the India. To cater our customer high volume requirements, we have dedicated each of our 6 manufacturing facilities to our 3 core product groups – APIs, Pelletization& Intermediates – reinforced by a well-equipped, centralized Research & Development laboratory.
We have been successfully supplying APIs all over the globe for more than 15 years. Total reactor volume exceeds 1200 KL which includes pilot and multi-purpose units. We are capable of executing extensive API requirements for our customers. Metrochem API Pvt Ltd has an experienced team of highly skilled chemists, experienced regulatory professionals and supply chain experts, who are ready to handle your API manufacturing requirements with expert care. We also offer Contract Manufacturing, Contract Research, and Custom Synthesis services. We have a stand-alone R&D center located in Hyderabad with State-of-the-art analytical facilities and over 90 scientists. We have extensively worked on and delivered new products across a wide variety of therapeutic segments and as a company, we have built strong expertise in new product development.